Table of ContentsDefinition / General
Cite this page: PCNA. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainspcna.html. Accessed April 23rd, 2017.
Definition / General
- Proliferating Cell Nuclear Antigen
- Also called cyclin
- Nonhistone 36 kDa nuclear protein with a role in DNA synthesis, DNA repair, and cell cycle progression
- Coordinates synthesis of both leading and lagging strands at the replication fork during DNA replication
- Expression correlates with proliferation activity