Table of ContentsDefinition / general
Cite this page: Pernick N. PCNA. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainspcna.html. Accessed November 21st, 2019.
Definition / general
- Proliferating Cell Nuclear Antigen
- Also called cyclin
- Nonhistone 36 kDa nuclear protein with a role in DNA synthesis, DNA repair, and cell cycle progression
- Coordinates synthesis of both leading and lagging strands at the replication fork during DNA replication
- Expression correlates with proliferation activity