Stains
PCNA


Topic Completed: 1 June 2005

Revised: 7 March 2019

Copyright: 2002-2015, PathologyOutlines.com, Inc.

PubMed Search: PCNA [title]

Nat Pernick, M.D.
Page views in 2018: 196
Page views in 2019 to date: 154
Table of Contents
Definition / general
Cite this page: Pernick N. PCNA. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainspcna.html. Accessed September 18th, 2019.
Definition / general
  • Proliferating Cell Nuclear Antigen
  • Also called cyclin
  • Nonhistone 36 kDa nuclear protein with a role in DNA synthesis, DNA repair, and cell cycle progression
  • Coordinates synthesis of both leading and lagging strands at the replication fork during DNA replication
  • Expression correlates with proliferation activity
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