Author: Nat Pernick, M.D. (see Authors page)

Revised: 7 December 2015, last major update June 2005

Copyright: (c) 2002-2015,, Inc.

PubMed Search: PCNA [title]

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Table of Contents
Definition / general
Cite this page: PCNA. website. Accessed January 22nd, 2019.
Definition / general
  • Proliferating Cell Nuclear Antigen
  • Also called cyclin
  • Nonhistone 36 kDa nuclear protein with a role in DNA synthesis, DNA repair, and cell cycle progression
  • Coordinates synthesis of both leading and lagging strands at the replication fork during DNA replication
  • Expression correlates with proliferation activity