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Helicobacter heilmannii gastritis

Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 6 August 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


● Very rare compared to H. pylori (Arch Pathol Lab Med 1995;119:1149)
● Patients usually symptomatic with dyspepsia, epigastric pain, acid reflux
● Associated with lymphoid hyperplasia, lymphoma, gastric carcinoma, peptic ulcer disease
● Less severe and fewer lymphoid aggregates than H. pylori gastritis (Mod Pathol 1999;12:534)
● More common in children; due to contact with farm animals or household pets
● Helical, 3.5-7.5 microns, 0.9 microns in diameter
● Prefers gastric antrum
H. felis, H. fennelliae, H. cinaedi also associated with human disease
● Treatment: same as H. pylori

Micro description

● Long tight spirals; thicker and twice as long as H. pylori and usually visible with H&E stain
● Changes similar to but less severe than H. pylori gastritis (lymphoid aggregates, scant neutrophils)

Micro images

Tightly coiled spiral organisms

Positive Stains

H. pylori (polyclonal antibody cross-reacts, but not monoclonal antibody), Warthin Starry, Steiner, Diff-Quik

Additional references

Odze R, Goldblum J. (2009). Surgical Pathology of the GI Tract, Liver, Biliary Tract, and Pancreas: expert consult - online and print. Philadelphia, PA: Saunders

End of Stomach > Infections > Helicobacter heilmannii gastritis

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