Helicobacter heilmannii

Last author update: 1 August 2012
Last staff update: 4 March 2022

Copyright: 2003-2023,, Inc.

PubMed Search: Helicobacter heilmannii gastritis

Elliot Weisenberg, M.D.
Page views in 2022: 2,829
Page views in 2023 to date: 2,714
Cite this page: Weisenberg E. Helicobacter heilmannii. website. Accessed September 30th, 2023.
Definition / general
  • Very rare compared to H. pylori (Arch Pathol Lab Med 1995;119:1149)
  • Patients usually symptomatic with dyspepsia, epigastric pain, acid reflux
  • Associated with lymphoid hyperplasia, lymphoma, gastric carcinoma, peptic ulcer disease
  • Less severe and fewer lymphoid aggregates than H. pylori gastritis (Mod Pathol 1999;12:534)
  • More common in children; due to contact with farm animals or household pets
  • Helical, 3.5 - 7.5 microns, 0.9 microns in diameter
  • Prefers gastric antrum
  • H. felis, H. fennelliae, H. cinaedi also associated with human disease
  • Same as H. pylori
Microscopic (histologic) description
  • Long tight spirals; thicker and twice as long as H. pylori and usually visible with H&E stain
  • Changes similar to but less severe than H. pylori gastritis (lymphoid aggregates, scant neutrophils)
Microscopic (histologic) images

Contributed by @liverwei on Twitter
Helicobacter heilmannii Helicobacter heilmannii Helicobacter heilmannii

Helicobacter heilmannii

Positive stains
  • H. pylori (polyclonal antibody cross-reacts, but not monoclonal antibody), Warthin Starry, Steiner, Diff-Quik
Board review style question #1

A 16 year old boy presents with dyspepsia and abdominal pain. Endoscopy shows nodular mucosa and histology (shown above) shows gastritis with prominent lymphoid aggregates and organisms on the mucosal surface (inset). What is your diagnosis?

  1. Atrophic gastritis
  2. Autoimmune gastritis
  3. Eosinophilic gastritis
  4. H. heilmannii gastritis
  5. H. pylori gastritis
Board review style answer #1
D. H. heilmannii gastritis

Comment Here

Reference: Helicobacter heilmannii
Back to top
Image 01 Image 02