Inflammatory / infectious


Topic Completed: 1 May 2007

Minor changes: 16 November 2020

Copyright: 2007-2021, PathologyOutlines.com, Inc.

PubMed Search: CMV cervix

Branko Perunovic, D.M.
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Cite this page: Perunovic B. CMV. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cervixcmv.html. Accessed December 3rd, 2021.
Definition / general
Case reports
  • No treatment in healthy people
Microscopic (histologic) description
  • Large, basophilic intranuclear inclusions or intracytoplasmic eosinophilic inclusions in occasional endocervical glandular epithelial cells
  • Inclusions also in endothelial and stromal cells but not squamous cells
  • Associated with fibrin thrombi, dense acute inflammatory infiltrate, lymphoid follicles, vacuoles in glandular cells, reactive changes in glandular epithelial cells
Microscopic (histologic) images

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Intracytoplasmic inclusions #1 (endocervical cells)

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#2 (endothelial cells)

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CMV+ glands and stroma

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Associated acute inflammatory infiltrate

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Intracytoplasmic vacuoles within endocervical glandular cells

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Fibrin thrombi within small vessels

Not cervix:
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Lung #1 - Giemsa stain

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Site unknown

Cytology description
  • Involvement of glandular and squamous cells
  • Cellular enlargement, nuclear enlargement and large nuclear inclusion surrounded by a halo "owl's eye"
  • Occasionally smaller nuclear or cytoplasmic inclusions
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