Other nonneoplastic

Apoptotic colopathy

Last author update: 1 May 2013
Last staff update: 3 May 2022

Copyright: 2003-2023,, Inc.

PubMed Search: Colon [title] bowel preparation

Hanni Gulwani, M.B.B.S.
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Cite this page: Gulwani H. Apoptotic colopathy. website. Accessed February 7th, 2023.
Microscopic (histologic) description
  • Reduced intracellular mucin, epithelial apoptosis and sloughing, increase in mitotic figures (Hum Pathol 1998;29:972, Cesk Patol 2011;47:130)
  • May have erosion of superficial epithelium, consistent with clinical impression of aphthoid ulcer
  • Also increased lymphocytes and neutrophils (Dis Colon Rectum 2006;49:109)
  • Patchy mononuclear infiltration in upper part of lamina propria, increased epithelial cell proliferation of individual crypts, basal cryptitis (Cesk Patol 2010;46:37)
  • Rarely lamina propria edema or extravasated red blood cells
Differential diagnosis
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