Eye

Lacrimal duct / gland

Adenoid cystic carcinoma



Last author update: 1 February 2014
Last staff update: 18 December 2020

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PubMed Search: Adenoid cystic carcinoma [title] lacrimal gland

Nat Pernick, M.D.
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Cite this page: Pernick N. Adenoid cystic carcinoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyelacrimaladenoidcystic.html. Accessed December 10th, 2022.
Definition / general
  • 20 - 30% of lacrimal gland tumors
  • Most common malignant tumor of lacrimal gland
  • Aggressive, may infiltrate eyelid or brain
Radiology images

AFIP images
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Serrated borders indicating infiltrative growth

Microscopic (histologic) description
  • Basaloid growth with cribriform change
  • Relatively bland cytology
  • Perineural invasion, focal tumor necrosis
Microscopic (histologic) images

AFIP images
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Infiltration of orbit

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Basaloid pattern

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Cribriform pattern


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Cylindromatous or sclerosing pattern

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Perineural invasion

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Metastasis to lung



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Classic pattern

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