Inflammatry disorders

Necrobiotic xanthogranuloma with paraproteinemia

Topic Completed: 1 February 2014

Minor changes: 24 December 2020

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PubMed Search: Necrobiotic xanthogranuloma with paraproteinemia of eyelid

Nat Pernick, M.D.
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Cite this page: Pernick N. Necrobiotic xanthogranuloma with paraproteinemia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyenecrobiotic.html. Accessed December 6th, 2021.
Definition / general
  • Multiple nodules or plaques in periorbital areas and elsewhere in body
  • Patients always have IgG paraprotein dysproteinemia
Microscopic (histologic) description
  • Granulomas with collagen necrobiosis, foamy macrophages, Touton giant cells
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