Heart & vascular pathology
Valvular disease
Lambl excrescence
Author: Nat Pernick, M.D.
Last author update: 1 May 2007
Last staff update: 26 January 2021
Copyright: 2003-2023, PathologyOutlines.com, Inc.
PubMed Search: Lambl excrescence
Table of Contents
Definition / general | Clinical images | Microscopic (histologic) description | Microscopic (histologic) images | Additional referencesCite this page: Pernick N. Lambl excrescence. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/hearttumorlamblexcrescence.html. Accessed September 21st, 2023.
Definition / general
- Also called valvular strands
- Common finding in elderly patients
- Small filiform / papillary processes that are age-related; may be organized mural thrombi at site of minor endothelial damage
- Associated with stroke, particularly among younger patients (Stroke 1997;28:2185)
- Aortic/pulmonic valves: most common at nodules of Aranti, along lines of closure and free cuspal edges
- Tricuspid/mitral valves: at site of valve closure on atrial surface
Clinical images
Contributed by Pallavi Khattar, M.D., Puneet Bedi, M.D. and John T. Fallon, M.D., Ph.D.
Papillary giant fibroelastoma of aortic valve
Microscopic (histologic) description
- Connective tissue / fibrin covered by endothelium
Microscopic (histologic) images
Contributed by Pallavi Khattar, M.D., Puneet Bedi, M.D. and John T. Fallon, M.D., Ph.D.
H&E
CD34
Elastin stain
S100
AFIP images
Finger-like projection
extending from valve
surface without branching
Additional references
