Other interstitial pneumonitis / fibrosis

Lipoid pneumonia

Topic Completed: 1 September 2011

Minor changes: 17 August 2020

Copyright: 2002-2021,, Inc.

PubMed search: lipoid pneumonia [title]

Nat Pernick, M.D.
Page views in 2020: 2,434
Page views in 2021 to date: 2,198
Cite this page: Pernick N. Lipoid pneumonia. website. Accessed October 15th, 2021.
Definition / general
  • Usually incidental post mortem finding associated with debilitating disease
  • Lipid either exogenous (from nasal sprays or inhalation of other lipid containing substances) or endogenous (bronchial obstruction)
Case reports
  • 1 year old man with recent history of meningitis with recurrent episodes of pneumonia (Case of the Week #287)
Gross description
  • Well circumscribed, firm with prominent lymphatics on lung surface in exogenous type
Gross images

Images hosted on other servers:
Yellow cut surface

Yellow cut surface

Microscopic (histologic) description
  • Lipoid material (or empty spaces), inflammatory cells and young fibroblasts
  • Reactive endarteritis, marked alveolar lining cell hyperplasia and lipid laden foamy macrophages
Microscopic (histologic) images

Case #287

Images hosted on other servers:
Aspiration pneumonia

Aspiration pneumonia

Foamy macrophages in alveolar spaces

Foamy macrophages in alveolar spaces

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