Lung

General

Patterns of injury



Topic Completed: 1 August 2011

Minor changes: 16 July 2020

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PubMed search: "patterns of injury" pulmonary

Elliot Weisenberg, M.D.
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Cite this page: Weisenberg E. Patterns of injury. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lungnontumorpatternsofinjury.html. Accessed October 25th, 2021.
Definition / general
  • Major categories of interstitial lung disease
  • Fibrosing: UIP, NSIP, COP, lung disease with connective tissue disease, pneumoconiosis, drug reaction, radiation pneumonitis
  • Granulomatous: sarcoidosis, hypersensitivity pneumonitis
  • Eosinophilic
  • Smoking related: DIP, respiratory bronchiolitis-associated interstitial lung disease
  • Other: pulmonary alveolar proteinosis
  • Source: Kumar et al.: Robbins and Cotran Pathologic Basis of Disease, 8th Edition, 2009

  • Intraalveolar reaction: DIP, pulmonary alveolar proteinosis, infection, extrinsic allergic alveolitis, chronic eosinophilic pneumonia
  • Small airway disease: bronchiolitis obliterans, respiratory bronchiolitis, mycoplasma infection, viral infection, extrinsic allergic alveolitis, eosinophilic pneumonia
  • Large airway disease: allergic bronchopulmonary aspergillosis, bronchocentric granulomatosis, TB, fungi, Granulomatosis with polyangiitis (Wegener's)
  • Granulomatous vasculitis: Granulomatosis with polyangiitis (Wegener's), sarcoidosis, Churg-Strauss, bronchocentric granulomatosis, fungi, TB
  • Small vessel disease: primary pulmonary hypertension, thromboembolism, polyarteritis nodosa, veno-occlusive disease, Churg-Strauss syndrome
  • Hemorrhage: Goodpasture's, SLE, immune complex glomerulonephritis, idiopathic pulmonary hemosiderosis, Granulomatosis with polyangiitis (Wegener's)
  • Lymphoid infiltrates: lymphocytic interstitial pneumonia, lymphoma, lymphoid aggregates, extrinsic allergic alveolitis
  • Eosinophils: chronic eosinophilic pneumonia, Churg-Strauss syndrome, bronchocentric granulomatosis, Langerhans cell histiocytosis
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