Small intestine & ampulla

Benign tumors / tumor-like conditions

Enteritis cystica profunda



Topic Completed: 1 August 2012

Minor changes: 19 November 2020

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PubMed Search: Enteritis cystica profunda small bowel

Hanni Gulwani, M.B.B.S.
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Cite this page: Gulwani H. Enteritis cystica profunda. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/smallbowelenteritiscystica.html. Accessed December 8th, 2021.
Definition / general
  • Mucosal glands and mucinous cysts in submucosa or deeper layer (J R Soc Med 2004;97:29, Arch Pathol Lab Med 2010;134:378)
  • Usually asymptomatic but may cause obstruction or intussuception
  • Pathogenesis: herniation, implantation after ulceration, mucosal microdiverticula and reepithelialization of fistulae (e.g. in Crohn's disease)
Microscopic (histologic) description
  • Mucosal glands and mucinous cysts in submucosa or deeper (subserosa) layer with hemosiderin, foreign body giant cells and lamina propria around the epithelium
Microscopic (histologic) images

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Mucin filled cysts (PAS diastase)

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