Stains & molecular markers

Topic Completed: 1 June 2013

Minor changes: 16 December 2020

Copyright: 2003-2021,, Inc.

PubMed Search: Fontana-Masson

Lauren N. Stuart, M.D., M.B.A.
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Cite this page: Stuart L. Fontana-Masson. website. Accessed January 19th, 2021.
Definition / general
  • Melanin stain
  • Interpretation: melanin granules reduce ammonia-silver nitrate and turn black, but difficult to interpret faint staining in sparsely positive cells
Microscopic (histologic) images

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Melanotic neuroectodermal tumor of infancy

Positive staining - normal
Positive staining - disease
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Image 01 Image 02