Stains
NeuN


Topic Completed: 1 September 2013

Minor changes: 7 March 2019

Copyright: 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: NeuN [title]

Nat Pernick, M.D.
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Page views in 2020 to date: 511
Cite this page: Pernick N. NeuN. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsneun.html. Accessed June 2nd, 2020.
Definition / general
  • Nuclear protein (neuronal nuclear antigen) widely expressed in mature postmitotic neurons and used as a biomarker for neurons (Wikipedia)
  • Is the FOX3 gene product (J Neurosci Methods 2005;148:26)
  • Considered a marker of neuronal differentiation in brain tumors; present in all major subtypes except pilocytic astrocytoma
Uses by pathologists
Microscopic (histologic) images

Images hosted on other servers:
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Section of cortex

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Middle temporal gyral neocortex

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Neuronal density changes

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Changes in neuronal size

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Neuropathological features

Positive staining - normal
  • Mature postmitotic neurons
Positive staining - disease
Negative staining
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