Stains & CD markers
OSCAR cytokeratin

Last author update: 1 July 2013
Last staff update: 25 June 2021

Copyright: 2003-2023,, Inc.

PubMed Search: CK Oscar, Oscar Keratin

Nat Pernick, M.D.
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Cite this page: Hamilton K, Pernick N. OSCAR cytokeratin. website. Accessed September 21st, 2023.
Definition / general
  • Also called CK Oscar or Oscar Keratin
  • Interpretation: cytoplasmic staining
Uses by pathologists
  • Broad spectrum keratin; distinguishes carcinomas from non-epithelial malignancies
Positive staining - normal
  • Epithelium of bile ducts, bladder (urothelium), breast ducts, bronchi, colorectum, duodenum, endometrium, ileum, ovary, pancreas, prostate, stomach and thyroid
  • Also hepatocytes, pituitary acini and pneumocytes
Positive staining - disease
Negative staining
  • Brain, endothelium, lymphocyte, muscle and nerves
  • GIST, lymphoma, melanoma, sarcoma and schwannoma
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