Stains & molecular markers
Thyroglobulin
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: Thyroglobulin[TI] review[PT] pathology
Thyroglobulin
Author: Nat Pernick, M.D.
Topic Completed: 1 June 2013
Minor changes: 25 September 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: Thyroglobulin[TI] review[PT] pathology
Cite this page: Pernick N. Thyroglobulin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsthyroglobulin.html. Accessed April 18th, 2021.
Definition / general
- Large glycoprotein (MW 670K) produced by thyroid follicular cells; later iodinated to form T3 and T4
- Specific marker of thyroid differentiation
Microscopic (histologic) images
Contributed by Andrey Bychkov, M.D., Ph.D.
Expression in thyroid
Easily leaks into soft tissue
Solid cell nests
AFIP images
Thyroid gland
signet ring
follicular adenoma
is thyroglobulin+
