Stains & CD markers
Thyroglobulin


Last author update: 1 June 2013
Last staff update: 21 June 2021

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PubMed Search: Thyroglobulin[TI] review[PT] pathology

Nat Pernick, M.D.
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Cite this page: Pernick N. Thyroglobulin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsthyroglobulin.html. Accessed February 3rd, 2023.
Definition / general
  • Large glycoprotein (MW 670K) produced by thyroid follicular cells; later iodinated to form T3 and T4
  • Specific marker of thyroid differentiation
Microscopic (histologic) images

Contributed by Andrey Bychkov, M.D., Ph.D.

Expression in thyroid

Easily leaks into soft tissue

Solid cell nests



AFIP images

Thyroid gland
signet ring
follicular adenoma
is thyroglobulin+

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