Thyroglobulin

Stains
Thyroglobulin

Author: Nat Pernick, M.D.

Topic Completed: 1 June 2013

Revised: 8 March 2019

Copyright: 2002-2017, PathologyOutlines.com, Inc.

Page views in 2019: 2,540

Page views in 2020 to date: 762

Table of Contents

Definition / general | Microscopic (histologic) images

Cite this page: Pernick N. Thyroglobulin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsthyroglobulin.html. Accessed April 6th, 2020.

Definition / general

Large glycoprotein (MW 670K) produced by thyroid follicular cells; later iodinated to form T3 and T4
Specific marker of thyroid differentiation

Microscopic (histologic) images

Images hosted on PathOut server:

Thyroid gland signet ring
follicular adenoma is thyroglobulin+

Courtesy of Andrey Bychkov, M.D., Ph.D.:

Expression in thyroid

Easily leaks into soft tissue

Solid cell nests