Stains
Thyroglobulin
Copyright: 2002-2017, PathologyOutlines.com, Inc.
Thyroglobulin
Author: Nat Pernick, M.D.
Topic Completed: 1 June 2013
Minor changes: 8 March 2019
Copyright: 2002-2017, PathologyOutlines.com, Inc.
Cite this page: Pernick N. Thyroglobulin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsthyroglobulin.html. Accessed July 7th, 2020.
Definition / general
- Large glycoprotein (MW 670K) produced by thyroid follicular cells; later iodinated to form T3 and T4
- Specific marker of thyroid differentiation
Microscopic (histologic) images
Images hosted on PathOut server:
Courtesy of Andrey Bychkov, M.D., Ph.D.:
Thyroid gland signet ring
follicular adenoma is thyroglobulin+
Courtesy of Andrey Bychkov, M.D., Ph.D.:
Expression in thyroid
Easily leaks into soft tissue
Solid cell nests
