Stains & CD markers
Thyroglobulin
Copyright: 2002-2025, PathologyOutlines.com, Inc.
PubMed Search: Thyroglobulin[TI] review[PT] pathology
Thyroglobulin
Author: Nat Pernick, M.D.
Last author update: 1 June 2013
Last staff update: 13 August 2025 (update in progress)
Copyright: 2002-2025, PathologyOutlines.com, Inc.
PubMed Search: Thyroglobulin[TI] review[PT] pathology
Cite this page: Pernick N. Thyroglobulin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsthyroglobulin.html. Accessed August 22nd, 2025.
Definition / general
- Large glycoprotein (MW 670K) produced by thyroid follicular cells; later iodinated to form T3 and T4
- Specific marker of thyroid differentiation
Microscopic (histologic) images
Contributed by Andrey Bychkov, M.D., Ph.D. and AFIP
Expression in thyroid
Easily leaks into soft tissue
Solid cell nests
Thyroid gland
signet ring
follicular adenoma
is thyroglobulin+
