Stains & CD markers
Thyroglobulin


Topic Completed: 1 June 2013

Minor changes: 21 June 2021

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PubMed Search: Thyroglobulin[TI] review[PT] pathology

Nat Pernick, M.D.
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Page views in 2022 to date: 198
Cite this page: Pernick N. Thyroglobulin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsthyroglobulin.html. Accessed January 21st, 2022.
Definition / general
  • Large glycoprotein (MW 670K) produced by thyroid follicular cells; later iodinated to form T3 and T4
  • Specific marker of thyroid differentiation
Microscopic (histologic) images

Contributed by Andrey Bychkov, M.D., Ph.D.

Expression in thyroid

Easily leaks into soft tissue

Solid cell nests



AFIP images

Thyroid gland
signet ring
follicular adenoma
is thyroglobulin+

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