Stains & CD markers

Topic Completed: 1 June 2013

Minor changes: 21 June 2021

Copyright: 2002-2021,, Inc.

PubMed Search: Thyroglobulin[TI] review[PT] pathology

Nat Pernick, M.D.
Page views in 2020: 3,026
Page views in 2021 to date: 2,448
Cite this page: Pernick N. Thyroglobulin. website. Accessed September 21st, 2021.
Definition / general
  • Large glycoprotein (MW 670K) produced by thyroid follicular cells; later iodinated to form T3 and T4
  • Specific marker of thyroid differentiation
Microscopic (histologic) images

Contributed by Andrey Bychkov, M.D., Ph.D.

Expression in thyroid

Easily leaks into soft tissue

Solid cell nests

AFIP images

Thyroid gland
signet ring
follicular adenoma
is thyroglobulin+

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