Topic Completed: 1 August 2012

Minor changes: 11 June 2021

Copyright: 2003-2021,, Inc.

PubMed Search: cytomegalovirus gastritis

Elliot Weisenberg, M.D.
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Cite this page: Weisenberg E. CMV. website. Accessed November 29th, 2021.
Definition / general
  • Generally associated with bone marrow transplants, AIDS, other immunosuppression
  • In pediatric population may be associated with hypertrophic gastropathy
  • Gastric involvement usually part of systemic disease
  • May cause perforation or fistulas
Microscopic (histologic) description
  • Eosinophilic intranuclear inclusions, variable granular purple cytoplasmic inclusions
  • Severe cases have ulceration, hemorrhage and perforation
Microscopic (histologic) images

Contributed by Andrey Bychkov, M.D., Ph.D. and Jijgee Munkhdelger, M.D., Ph.D.

CMV gastritis ulcer

CMV gastritis IHC

CMV infected cells

Classic cytomegalic cell

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Duodenal biopsy

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