Thyroid gland
Thyroiditis
Autoimmune thyroiditis



Topic Completed: 1 March 2009

Minor changes: 12 March 2019

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PubMed Search: autoimmune thyroiditis thyroid

Shahid Islam, M.D., Ph.D.
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Cite this page: Islam S. Autoimmune thyroiditis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/thyroidautoimmune.html. Accessed May 30th, 2020.
Definition / general
  • Nonneoplastic thyroid disorders with antithyroid antibodies and associated with specific HLA haplotypes
  • #1 cause of hypothyroidism in iodine sufficient areas
  • Includes Graves' disease, Hashimoto's thyroiditis and most forms of thyroiditis in this section except infectious
  • Rosai differentiates based on follicular epithelium: lymphocytic thyroiditis if relatively normal follicles, Hashimoto's thyroiditis if oncocytic change, Graves' disease if diffusely hyperplastic follicles
Epidemiology
Clinical features
  • May be due to disturbance in suppressor T cells
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