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Histology topic template

Revised: 5 August 2020
Copyright: 2020, PathologyOutlines.com, Inc.

    Example of well written Histology topic: Adrenal gland and paraganglia - Adrenal medulla

    Ideally chapters should have only one histology topic rather than one topic for each cell type or part of the organ. It may be appropriate to have a separate bulleted subsection for each cell type or part of the organ within the different sections.

    For ease of use, we put topic headings in the same order. Please put some text under each heading, but do not include obvious or repetitive information. If you think there is nothing to add, please write "not relevant to this topic", "repetitive with __ heading" or "unknown at this time". Do not delete any topic headings.


    Author 1

    Author name with degrees: ___________________________________________

    Author rank (M.D. candidate / Resident / Fellow / Instructor / Assistant, Associate or Full Professor): ___________________________________________

    Author leadership roles (maximum of 2) (ex: Director of Surgical Pathology, Vice Chair of Anatomic Pathology, Director of Cytopathology): ___________________________________________

    Author institution name: ___________________________________________

    Author institution city, state, zip code and country: ___________________________________________

    Author email address: ___________________________________________


    Author 2

    Author name with degrees: ___________________________________________

    Author rank (Assistant, Associate or Full Professor): ___________________________________________

    Author leadership roles (maximum of 2) (ex: Director of Surgical Pathology, Vice Chair of Anatomic Pathology, Director of Cytopathology): ___________________________________________

    Author institution name: ___________________________________________

    Author institution city, state, zip code and country: ___________________________________________

    Author email address: ___________________________________________



    Chapter name: ___________________________________________

    Section and subsection (in the Table of Contents): ___________________________________________

    Topic name: Histology



    Definition / general
    A 1 - 2 sentence summary of the topic.

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    Essential features
    This topic heading should be completed after the rest of the topic is finished, and should duplicate the 3 - 5 most important points mentioned elsewhere in the topic. In other words, it should list what every pathologist should know about the topic or what would be in a Board Review book.

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    Terminology
    Other names used today or historically that pathologists may be more familiar with.

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    Physiology
    Step by step details of the normal functions of the tissue / organ.

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    Diagrams (optional)
    Those that don't automatically fit in another section. For diagrams you submit, provide a brief 1 - 4 word caption to appear below the thumbnail of the image and a longer figure legend to appear when the image is opened. If you do not have your own images, provide links to journal images with a brief 1 - 4 word caption.


    Clinical features (optional)
    Anything clinical not included above or below. Includes associations with other conditions.

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    Laboratory
    Typical laboratory tests (ex: serology) used to evaluate the function of the tissue / organ.

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    Gross description
    Description of the excised tissue / organ.

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    Gross images
    Images of the excised specimen. For images you submit, provide a brief 1 - 4 word caption to appear below the thumbnail of the image and a longer figure legend to appear when the image is opened. If you do not have your own images, provide links to journal images with a brief 1 - 4 word caption.


    Frozen section description (optional)
    Description of the tissue at frozen section, focusing on features relevant to the intraoperative differential diagnosis.

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    Frozen section images (optional)
    Images of the specimen at frozen section. Touch preparations and smears should not be in this section (include in cytology images). For images you submit, provide a brief 1 - 4 word caption to appear below the thumbnail of the image and a longer figure legend to appear when the image is opened.


    Microscopic (histologic) description
    List microscopic features for each cell type.

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    Microscopic (histologic) images
    The author must take and submit high quality representative micro images. Include low and high power H&E images and relevant immunostains and special stains. For each image, submit both a caption and a figure legend in the manuscript word document. Do not include your name, twitter handle, institution or logo on the image. The caption will appear below the thumbnail of the image and should be 1 - 4 words describing the image findings, such as "Cytologic atypia", "Chronic inflammation", "Epithelioid cells", "Chromogranin" or "AE1 / AE3". Do not use captions such as "Case 1", "Various images", "H&E" or "100x". The figure legend will appear when the image is open and must contain all relevant information including site, procedure, diagnosis, key histologic findings and stain if other than H&E. Do not use figure legends such as "Case 1" or "Representative images". We will remove all existing outside micro images.


    Virtual slides
    Please check these sites: University of Toronto, University of Michigan. Provide a brief 1 - 4 word caption for each slide. If no virtual slides found, please advise. Please limit virtual slides to 6 per topic and only include the most relevant / representative slides.


    Cytology description (optional)
    Cytologic features.

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    Cytology images (optional)
    For images you submit, provide a brief 1 - 4 word caption to appear below the thumbnail of the image and a longer figure legend to appear when the image is opened. If you do not have your own images, provide links to journal images with a brief 1 - 4 word caption. Include preparation, i.e. Pap, Diff-Quik, cell block, H&E touch, H&E smear. Contact us if you need help obtaining images.


    Positive stains
    Provide a list of the names of relevant IHC and special stains for each cell type that are positive at least 50% of the time. Stains that are predominantly negative should go in the negative stains section. Begin each bullet with the name(s) of the stain(s). List those most commonly used first. If not uniformly positive, provide percentage of cases. List staining patterns if uncommon.

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    Negative stains
    Include relevant IHC and special stains for each cell type. List most commonly used first. If not uniformly negative, provide percentage of cases. List staining patterns if uncommon.

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    Electron microscopy description
    Electron microscopy diagnostic findings.

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    Electron microscopy images
    Electron microscopy images. For images you submit, provide a brief 1 - 4 word caption to appear below the thumbnail of the image and a longer figure legend to appear when the image is opened. If you do not have your own images, provide links to journal images with a brief 1 - 4 word caption.


    Videos
    Links to YouTube or other sites or create your own (preferably 5 minutes or less). Provide a caption for each video. Dr. Gardner has many skin and soft tissue videos on his YouTube page.


    Additional references
    General references for this topic not included above.

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    Board Review Question(s)
    Prepare 2 board review style questions that highlight important content from this topic. These are not actual questions from the Pathology boards but review questions written in a similar format. The questions should test basic, essential diagnostic concepts that all pathologists should know rather than minor details. The tested concepts should come from the Essential features, Microscopic description or Positive / Negative stains sections. All information relevant to correct and incorrect answers should be found in the topic. The first question must contain an image of the tissue / organ followed by a multiple choice question, such as "Which of the following is true about XXX tissue / organ?" The image can be reused from the topic. Do not use the format "Which of the following is false?" Questions should have only one answer. Do not use responses "all of the above", "none of the above", "A and C", etc. This question will be part of our Board Review page so the reader will not know the topic with which it is associated. Therefore you must make the organ clear in the question and the diagnosis clear in the answer. The second question may have an image associated with it but an image is not required. Click here for examples.


    Board Review Answer(s)
    Answers to the Question(s) above, sorted alphabetically by the first letter in the answer.