Colon nontumor
Colitis (noninfectious)
Diversion colitis



Topic Completed: 1 May 2013

Revised: 8 January 2019, last major update May 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: diversion colitis

Hanni Gulwani, M.B.B.S.
Page views in 2018: 2,663
Page views in 2019 to date: 1,626
Cite this page: Gulwani H. Diversion colitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colondiversion.html. Accessed July 22nd, 2019.
Definition / general
  • Also called defunctionalized bowel
  • Due to dietary deprivation of short chain fatty acids normally produced by colonic bacteria, important for caloric supply of colonic enterocytes
  • Similar histologic features regardless of cause for diversion, although patients with inflammatory bowel disease (IBD) may have superimposed IBD histologic changes
  • In children, resembles normal appendix (Histopathology 2000;36:41, Hum Pathol 1993;24:211)
Etiology
  • Ileostomy, colostomy, other surgical diversion
Clinical features
  • Symptoms varies from none to severe diarrhea resembling ulcerative colitis
Diagnosis
  • Can only diagnose with confidence if colon was noninflamed at time of surgical diversion
Case reports
Treatment
Gross description
  • Varies from minimal mucosal friability to ulceration
Microscopic (histologic) description
  • Marked lymphoid hyperplasia resembling follicular proctitis or aphthous lesions, initially in lamina propria but later transmural (Am J Surg Pathol 1990;14:548, Hum Pathol 1990;21:429)
  • Mild colitis with crypt abscesses
  • Late in disease develop muscularis mucosa hypertrophy, fatty and fibrous infiltration of submucosa, thickened muscularis propria and narrow lumen (Colorectal Dis 2007;9:601); no architectural distortion
Microscopic (histologic) images

Images hosted on other servers:

Diversion proctitis with diffuse chronic
inflammation of lamina propria and crypt
abscesses but no architectural distortion

Back to top