Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 23 February 2013, last major update December 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Remnants, implants or accessory nodules that may appear from angle of mandible to thyroid gland, most commonly at level of thyroid gland
● Rarely becomes hyperplastic or neoplastic
● Usually an incidental finding during thyroid surgery in preteens, very rare in adults due to thymic involution
● 12 month old boy with neck mass
(Arch Pathol Lab Med 2001;125:278)
● 22 year old woman with anterior neck mass (Arch Pathol Lab Med 2001;125:842)
● With micronodular epithelial hyperplasia (Int J Surg Pathol 2006;14:73)
Homogeneous mass in submandibular space, extending toward parapharyngeal space
● Normal appearing thymic tissue
Central cervical epithelial rest
CK5/6, p63, CD10
● Other heterotopic epithelial elements, including misplaced cutaneous structures and salivary gland tissue
(Am J Clin Pathol 2009;132:707)
● Ectopic cervical thymoma: "the great mimic"; considered in differential diagnosis of neck masses in elderly (Indian J Pathol Microbiol 2007;50:553)
End of Mediastinum > Thymus > Ectopic thymus
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