Bone marrow neoplastic
Bone marrow - neoplastic myeloid
MDS / MPN
WHO classification - MDS / MPN


Topic Completed: 1 August 2011

Minor changes: 19 June 2020

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PubMed Search: WHO classification MDS/MPN [title]


Nikhil Sangle, M.D.
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Cite this page: Sangle N. WHO classification - MDS / MPN. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/myeloproliferativewhomdsmpnwho.html. Accessed August 10th, 2020.
Definition / general
  • World Health Organization (WHO) classification of disorders which bridge the myelodysplastic (MDS) and myeloproliferative neoplasm (MPN) categories at initial presentation
  • Have morphologic dysplasia and proliferative advantage of one or more of the myeloid differentiating cell lines
  • Diagnosis requires correlation of bone marrow and peripheral blood findings with clinical, genetic and other laboratory information (Semin Diagn Pathol 2003;20:154)
World Health Organization classification
WHO 2008 classification
  • 4.1 Chronic myelomonocytic leukemia
  • 4.2 Juvenile myelomonocytic leukemia
  • 4.3 Atypical chronic myeloid leukemia
  • 4.4 MDS/MPN, unclassifiable

WHO 2001 classification
  • Atypical chronic myeloid leukemia
  • Chronic myelomonocytic leukemia
  • Juvenile myelomonocytic leukemia
  • Myelodysplastic / myeloproliferative disease, unclassifiable
Additional references
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