Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Small bowel (small intestine)

Other / benign tumors and tumor-like conditions

Leiomyoma


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 22 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Benign smooth muscle tumors that arise from small bowel muscularis propria or muscular mucosa
● Duodenal leiomyomas of muscular mucosa are incidental, 1-2 mm, merge with muscularis mucosa; those not from muscularis mucosa are also often incidental but larger, 2-4 cm, with firm, white, whorled cut surface

Micro description
=========================================================================

● Low cellularity, no/rare mitotic figures, resembles esophageal leiomyoma

Micro images
=========================================================================



Esophageal leiomyomas

Positive stains
=========================================================================

● Smooth muscle actin, desmin

Negative stains
=========================================================================

● CD117, CD34

Differential diagnosis
=========================================================================

GIST: often cytologically malignant in small bowel; CD117+, often CD34+ (Rom J Morphol Embryol 2011;52:1121, Am J Surg Pathol 2003;27:625)

End of Small bowel (small intestine) > Other / benign tumors and tumor-like conditions > Leiomyoma


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).