Table of ContentsDefinition / general | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Negative stains | Differential diagnosis
Cite this page: Gulwani H. Leiomyoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/smallbowelleiomyoma.html. Accessed April 1st, 2023.
Definition / general
- Benign smooth muscle tumors that arise from small bowel muscularis propria or muscular mucosa
- Duodenal leiomyomas of muscular mucosa are incidental, 1 - 2 mm, merge with muscularis mucosa; those not from muscularis mucosa are also often incidental but larger, 2 - 4 cm, with firm, white, whorled cut surface
Microscopic (histologic) description
- Low cellularity, no / rare mitotic figures, resembles esophageal leiomyoma
- GIST: often cytologically malignant in small bowel; CD117+, often CD34+ (Rom J Morphol Embryol 2011;52:1121, Am J Surg Pathol 2003;27:625)