Small bowel (small intestine)

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 13 October2015, last major update August 2012

Copyright: (c) 2003-2015,, Inc.

PubMed Search: lymphangiectasia
  • Primary intestinal lymphangiectasia is rare disorder of dilated intestinal lacteals resulting in lymph leakage into the small bowel lumen, causing protein-losing enteropathy leading to lymphopenia, hypoalbuminemia and hypogammaglobulinemia (Orphanet J Rare Dis 2008;3:5, eMedicine)
  • Dilation of lymphatics in mucosa, submucosa or subserosa
  • Primary: children, due to congenital obstructive defective in lymphatics
  • Secondary: due to constrictive pericarditis, Crohn’s (Virchows Arch 2008;452:57), intestinal malignancy, myocardial disease, pancreatitis, retroperitoneal fibrosis, sarcoidosis, Waldenström macroglobulinemia
  • Resection, treatment of underlying conditions
Clinical Images

Markedly dilated lymphatics

Micro Images

Markedly dilated lymphatics

Courtesy of Dr. Semir Vranic