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Small bowel (small intestine)

Malabsorption

Lymphangiectasia


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 22 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Primary intestinal lymphangiectasia is rare disorder of dilated intestinal lacteals resulting in lymph leakage into the small bowel lumen, causing protein-losing enteropathy leading to lymphopenia, hypoalbuminemia and hypogammaglobulinemia (Orphanet J Rare Dis 2008;3:5, eMedicine)
● Dilation of lymphatics in mucosa, submucosa or subserosa
Primary: children, due to congenital obstructive defective in lymphatics
Secondary: due to constrictive pericarditis, Crohn’s (Virchows Arch 2008;452:57), intestinal malignancy, myocardial disease, pancreatitis, retroperitoneal fibrosis, sarcoidosis, Waldenström macroglobulinemia

Treatment
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● Resection, treatment of underlying conditions

Clinical images
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Markedly dilated lymphatics

Micro images
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Markedly dilated lymphatics

End of Small bowel (small intestine) > Malabsorption > Lymphangiectasia


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