Cite this page: Lymphangiectasia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowellymphangiectasia.html. Accessed December 9th, 2016.
Definition / General
- Primary intestinal lymphangiectasia is rare disorder of dilated intestinal lacteals resulting in lymph leakage into the small bowel lumen, causing protein-losing enteropathy leading to lymphopenia, hypoalbuminemia and hypogammaglobulinemia (Orphanet J Rare Dis 2008;3:5, eMedicine)
- Dilation of lymphatics in mucosa, submucosa or subserosa
- Primary: children, due to congenital obstructive defective in lymphatics
- Secondary: due to constrictive pericarditis, Crohn’s (Virchows Arch 2008;452:57), intestinal malignancy, myocardial disease, pancreatitis, retroperitoneal fibrosis, sarcoidosis, Waldenström macroglobulinemia
- Resection, treatment of underlying conditions