Small bowel (small intestine)
Benign tumors and tumor-like conditions
Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 22 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
● Also called lymphoid polyp; formerly called pseudolymphoma
● Most common site is ileocecal region
● Causes intussusception in children
● Nodular lymphoid hyperplasia: nodules throughout bowel, associated with giardiasis or childhood viral infection
● 60 year old woman with florid reactive lymphoid hyperplasia of terminal ileum (BMJ Case Rep. 2010;2010 Epub 2010 Jan 13.)
Terminal ileum exhibiting shows mucosal ulcers due to nodular lymphoid hyperplasia
● Numerous lymphoid follicles with germinal centers in lamina propria or submucosa
● CD20, CD45; do not confuse BCL2 expression in marginal zone cells with BCL2 expresion of germinal center cells in follicular lymphoma (Am J Surg Pathol 2003;27:888)
● Low grade lymphoma: often infiltrative, light chain restriction
End of Small bowel (small intestine) > Benign tumors and tumor-like conditions > Lymphoid hyperplasia
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