Small intestine & ampulla

Benign tumors / tumor-like conditions

Lymphoid hyperplasia

Topic Completed: 1 August 2012

Minor changes: 19 April 2021

Copyright: 2003-2021,, Inc.

PubMed Search: Lymphoid hyperplasia[TI] small bowel

Hanni Gulwani, M.B.B.S.
Page views in 2020: 4,360
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Cite this page: Gulwani H. Lymphoid hyperplasia. website. Accessed December 8th, 2021.
Definition / general
  • Also called lymphoid polyp; formerly called pseudolymphoma
  • Most common site is ileocecal region
  • Causes intussusception in children
  • Nodular lymphoid hyperplasia: nodules throughout bowel, associated with giardiasis or childhood viral infection
Case reports
Gross images

Images hosted on other servers:

Terminal ileum exhibiting
shows mucosal ulcers
due to nodular lymphoid

Microscopic (histologic) description
  • Numerous lymphoid follicles with germinal centers in lamina propria or submucosa
Microscopic (histologic) images

Images hosted on other servers:

Various images

Positive stains
Differential diagnosis
  • Low grade lymphoma: often infiltrative, light chain restriction
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