Soft tissue
Adipose tissue
Myolipoma

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 4 August 2016, last major update August 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Myolipoma

Definition / General
Terminology
  • Called lipoleiomyoma in uterus
  • Note: myelolipoma is tumor with hematopoietic (including myeloid) elements, often in adrenal gland
Epidemiology
  • Very rare tumor of adults in abdomen, retroperitoneum or abdominal wall
  • Other rare sites include eyelid, pericardium, base of tongue
Case Reports
Treatment
  • Excision
  • Does not recur, metastasize or transform
Gross Description
  • Often 9 cm or more, completely or partially encapsulated, yellow-white
Gross Images

Images hosted on other servers:

Fatty tissue with bands and nodules of firm white tissue

Micro Description
  • Mature adipose tissue and mature (well differentiated) smooth muscle in short fascicles (Stanford University)
  • Variable fibrosis and inflammation
  • No floret cells, no thick walled vessels, no necrosis, no mitotic figures
Micro Images

Images hosted on other servers:

Mature fat and smooth muscle fibers

Low magnification view of myolipoma

Smooth muscle fibers are SMA+ (left), desmin+ (right)

Positive Stains
Differential Diagnosis