All cases are archived on our website. To view them sorted by number, diagnosis or category, visit our Home Page and click on the Case of the Week button on the left hand side. To subscribe or unsubscribe to the Case of the Week or our other email lists, click here.
Thanks to Dr. Samir Ghani, Wexham Park Hospital (United Kingdom), for contributing this case and the discussion. To contribute a Case of the Week, follow the guidelines on our Case of the Week page.
(1) We are continously updating topics in our Stains and CD Markers chapters. However, there are over 600 stains / CD Marker topics, so we are seeking pathologists interested in reviewing 3-5 of these topics. If interested, please contact Kristina at firstname.lastname@example.org.
(2) We have recently changed the colors for visited links on our updated pages. As always, links to subscription based journals are navy and links to free full text references are green. Now when you click on them, they will turn to a lighter shade of blue and green. We hope this will make it easier to keep track of which links have been viewed.
(3) Our Case of the Week page now lists upcoming cases with the contributor's name and the number of cases pending in our queue. Currently, we have a 8-9 month turn around time from when we accept a case to when it is posted on our website. We now are only posting a maximum of 5 cases per contributor per calendar year.
(4) We have a new Microbiology chapter that is being written by Christopher Hale, M.D. Be sure to take a look!
Case of the Week #285
A 41 year old woman delivered a full term baby
without complications and underwent tubal ligation and greater omentum
sampling during a Caesarean section.
What is your diagnosis?
Extra uterine deciduosis
The omentum and the peritoneal surface of the fallopian tube show
exaggerated Extra-Uterine Deciduosis (EUD) / decidual reaction, with single / cell aggregates displaying vacuolated cytoplasm with mucoid-like material and bland nuclear morphology. No mitotic figures are seen. There are only a few cells with eosiophilic cytoplasm, which provide the clue to the nature of the lesion, in addition to the clinical presentation.
Immunohistochemistry showed strong progesterone receptor nuclear staining in the
lesional cells. The vimentin stain was diffusely positive. Other markers such
as EMA and Calretinin were negative (not shown).
Deposits are found mainly on the ovary and cervix, but also on abdominal serosal surfaces of the fallopian tubes, bowel, peritoneum and vagina, as well as lungs, pleura, retroperitoneal lymph nodes and rarely skin. Most lesions do not require further treatment and spontaneously involute within 4-6 weeks of delivery.
Nat Pernick, M.D., President
and Palak Thakore, Associate Medical Editor
30100 Telegraph Road, Suite 408
Bingham Farms, Michigan (USA) 48025
Alternate email: NatPernick@gmail.com