Liver & intrahepatic bile ducts

Systemic conditions

Congestive heart failure

Topic Completed: 1 May 2012

Minor changes: 22 September 2020

Copyright: 2002-2021,, Inc.

PubMed Search: Congestive heart failure[TI] liver[TI]

Komal Arora, M.D.
Page views in 2020: 1,972
Page views in 2021 to date: 1,679
Cite this page: Arora K. Congestive heart failure. website. Accessed October 15th, 2021.
Definition / general
  • Also called cardiac sclerosis
  • Mild elevation of serum ALT and AST, mild jaundice
  • Rarely progresses to fully developed cirrhosis
Microscopic (histologic) description
  • Centrilobular congestion and necrosis, central stellate fibrosis
  • Sinusoidal dilation which can compress liver cell plates, hemosiderin and lipochrome laden macrophages
  • May have cholestasis at edge of fibrotic zone, PAS+ globules in ischemic central zones
  • Portal tracts spared until late
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