Liver & intrahepatic bile ducts

Systemic conditions

Congestive heart failure

Last author update: 1 May 2012
Last staff update: 28 June 2022

Copyright: 2002-2022,, Inc.

PubMed Search: Congestive heart failure[TI] liver[TI]

Komal Arora, M.D.
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Cite this page: Arora K. Congestive heart failure. website. Accessed August 17th, 2022.
Definition / general
  • Also called cardiac sclerosis
  • Mild elevation of serum ALT and AST, mild jaundice
  • Rarely progresses to fully developed cirrhosis
Microscopic (histologic) description
  • Centrilobular congestion and necrosis, central stellate fibrosis
  • Sinusoidal dilation which can compress liver cell plates, hemosiderin and lipochrome laden macrophages
  • May have cholestasis at edge of fibrotic zone, PAS+ globules in ischemic central zones
  • Portal tracts spared until late
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