Liver & intrahepatic bile ducts
Systemic conditions
Congestive heart failure
Author: Komal Arora, M.D.
Topic Completed: 1 May 2012
Minor changes: 22 September 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: Congestive heart failure[TI] liver[TI]
Cite this page: Arora K. Congestive heart failure. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/liverCHF.html. Accessed April 10th, 2021.
Definition / general
- Also called cardiac sclerosis
- Mild elevation of serum ALT and AST, mild jaundice
- Rarely progresses to fully developed cirrhosis
Microscopic (histologic) description
- Centrilobular congestion and necrosis, central stellate fibrosis
- Sinusoidal dilation which can compress liver cell plates, hemosiderin and lipochrome laden macrophages
- May have cholestasis at edge of fibrotic zone, PAS+ globules in ischemic central zones
- Portal tracts spared until late
