Mandible & maxilla

Benign odontogenic tumors

Squamous odontogenic tumor



Last author update: 1 January 2004
Last staff update: 23 August 2022

Copyright: 2004-2022, PathologyOutlines.com, Inc.

PubMed Search: Squamous odontogenic tumor (mandible OR maxilla)


Nat Pernick, M.D.
Page views in 2021: 2,775
Page views in 2022 to date: 2,759
Cite this page: Pernick N. Squamous odontogenic tumor. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/mandiblemaxillasquamousodon.html. Accessed December 3rd, 2022.
Definition / general
  • Uncommon
  • Most common in 20s but occurs in all ages, 2/3 male
  • Usually in anterior maxilla or posterior mandible in soft tissue or bone; 25% are multiple lesions
  • Arises from rests of Malassez in periodontal ligament
  • Low probability of recurrence, no malignant transformation reported
Radiology description
  • Well circumscribed
  • Semicircular radiolucency
  • Sclerotic border
  • Near teeth roots
Case reports
Treatment
  • Excision with extraction of involved teeth or en bloc resection
Microscopic (histologic) description
  • Anastomosing islands of benign, stratified squamous epithelium within fibrous stroma, often well defined nests with clear cells
  • May contain keratin or psammoma bodies
  • Often epithelial vacuolization and microcysts
  • No atypia, no mitotic figures, no inflammation, no peripheral palisading
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Squamous odontogenic tumor

Squamous odontogenic tumor

SOT at scanning magnification

SOT at scanning magnification

Benign islands of squamous epithelium within fibrous stroma Benign islands of squamous epithelium within fibrous stroma

Benign islands of squamous epithelium within fibrous stroma


Epithelial vacuolization of squamous islands

Epithelial vacuolization of squamous islands

Intraepithelial calcifications

Intraepithelial calcifications

Rounded contours of nests

Rounded contours of nests

Differential diagnosis
Additional references
Back to top
Image 01 Image 02