Skin nontumor
Spongiotic, psoriasiform and pustular reaction patterns
Lichen simplex chronicus
Topic Completed: 1 August 2011
Minor changes: 18 March 2020
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PubMed Search: Lichen simplex chronicus [title]
Table of Contents
Definition / general | Terminology | Clinical features | Microscopic (histologic) description | Additional referencesCite this page: Hamodat M. Lichen simplex chronicus. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skinnontumorlichensimplexchronicus.html. Accessed January 22nd, 2021.
Definition / general
- Plaque like condition due to chronic rubbing and scratching
Terminology
- Also called neurodermatitis
Clinical features
- Thick, scaly plaques with erythema, well demarcated from surrounding skin
- Associated with excoriation, lichenification, crusting
- Raised nodules are called prurigo nodularis
Microscopic (histologic) description
- Marked hyperkeratosis associated with foci of parakeratosis
- Prominent granular cell layer
- The epidermal rete are elongated and irregularly thickened
- Mild spongiosis
- Perivascular and interstitial inflammation with histiocytes, lymphocytes and occasional eosinophils in superficial dermis
- Occasionally enlarged elongated myofibroblasts, papillary dermal fibrosis, nerve hyperplasia
Additional references
