Table of Contents
Definition / general | Case reports | Treatment | Microscopic (histologic) description | Microscopic (histologic) images | Board review style question #1 | Board review style answer #1Cite this page: Hale CS. Lymphangioma / lymphatic malformation. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticlymphangioma.html. Accessed March 22nd, 2023.
Definition / general
- Usually infants or children age 5 years or less
- Neck, axilla, breast, chest, buttock, thigh
- Either superficial (lymphangioma circumscriptum, associated with surgery or radiotherapy for breast carcinoma), cystic (cystic hygroma) or deep (lymphangioma cavernosum)
Case reports
- 52 year old woman with multiple vulval lesions and a history of itching (Case of the Week #472)
Treatment
- Excision, but 25% recur
Microscopic (histologic) description
- Grouped translucent papules with thin vascular lumina that impinge on epidermis
- Often deep remnants in subcutaneous tissue
Board review style question #1
Which of the following statements is true regarding lymphatic malformations?
A. They typically arise in senior adults
B. They are unaffected by hormonal changes
C. They may recur after excision
D. They are distinctive and unlikely to be confused with other entities
A. They typically arise in senior adults
B. They are unaffected by hormonal changes
C. They may recur after excision
D. They are distinctive and unlikely to be confused with other entities
Board review style answer #1
C. They may recur after excision. Lymphatic malformations are congenital and usually detected at birth or in the first few years of life. They may be affected by pubertal or pregnancy related hormones. There is a broad differential diagnosis including (acquired) lymphangiectasia, metastatic carcinoma, verrucae, molluscum, hemangioma, angiokeratoma and lymphangioendothelioma.
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Reference: Skin nonmelanocytic tumor > Lymphangioma / lymphatic malformation
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Reference: Skin nonmelanocytic tumor > Lymphangioma / lymphatic malformation