Cervix
Benign / nonneoplastic lesions
Blue nevus

Author: Branko Perunovic, M.D. (see Authors page)

Revised: 14 April 2017, last major update May 2007

Copyright: (c) 2007-2017, PathologyOutlines.com, Inc.

PubMed Search: Blue nevus cervix

Cite this page: Blue nevus. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixbluenevus.html. Accessed December 14th, 2017.
Definition / general
  • Present in up to 2% of cervices; may be more common in Japanese women, particularly if step sections are obtained (Acta Pathol Jpn 1991;41:751)
  • 20% are multiple
  • Usually an incidental finding
Case reports
Gross description
  • Blue / black, flat up to 3 cm
  • Usually ill defined in lower endocervix
Microscopic (histologic) description
  • Elongated, wavy dendritic cells in clusters or individually, below endocervical epithelium
  • Cytoplasm has brown melanin
  • Stromal macrophages
Microscopic (histologic) images

Images hosted on PathOut server:

Pigment containing nevus cells in cervical stroma

Positive stains
Negative stains
Electron microscopy description
Differential diagnosis
  • Hemosiderin: coarse granules are refractile and iron+, Fontana-Masson negative; pigment is in macrophages, not spindle cells
  • Melanoma: junctional change, stromal infiltration by malignant cells
  • Melanosis: basal epithelium only, not in stroma
Additional references