Other mediastinal carcinoma
Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 9 March 2013, last major update December 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Most mediastinal epithelial neoplasms are metastases, usually from trachea, bronchi, lung, esophagus
- Usually rapidly fatal
- Primary lung tumors may present as huge mediastinal mass with occult bronchial primary
Electron microscopy description
- CD5 (suggestive of thymic), PLAP (germ cell), PSA (prostate), S100 (melanoma, others), thyroglobulin (thyroid)
End of Mediastinum > Other mediastinal carcinoma > Metastatic carcinoma
- Premelanosomes suggests melanoma
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