Pancreas
Neuroendocrine neoplasms
Somatostatinoma

Author: Deepali Jain, M.D. (see Authors page)

Revised: 22 December 2017, last major update August 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Somatostatinoma[TI] pancreas

Cite this page: Jain, D. Somatostatinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/pancreassomatostatin.html. Accessed August 20th, 2018.
Definition / general
Clinical features
  • Only rarely associated with somatostainoma syndrome (diabetes, cholecystolithiasis, steatorrhea, hypochlorhydria, Endocr Relat Cancer 2008;15:229)
  • Hard to localize preoperatively
  • May be in duodenal wall
  • May have psammoma bodies
Clinical images

Images hosted on other servers:

Duodenal tumor endoscopy

Microscopic (histologic) images

Images hosted on PathOut server:

AFIP images:

Pancreatic somatostatinoma

Tumor of uncertain malignant potential

Small cell carcinoma



Images hosted on other servers:

Somatostatin+ cells

Paraganglioma-like growth pattern

Various images


Duodenal tumors

Electron microscopy images

Images hosted on PathOut server:

AFIP images:

Ultrastructural appearance of somatostatinoma