Small intestine & ampulla
General
WHO classification

Editor-in-Chief: Debra Zynger, M.D.
Raul S. Gonzalez, M.D.

Topic Completed: 15 September 2020

Minor changes: 15 September 2020

Copyright: 2020, PathologyOutlines.com, Inc.

PubMed Search: WHO classification[TIAB] (small intestine OR ampulla)

Raul S. Gonzalez, M.D.
Page views in 2020 to date: 21
Table of Contents
Definition / general | WHO (2019)
Cite this page: Gonzalez RS. WHO classification. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelWHOclassification.html. Accessed September 29th, 2020.
Definition / general
  • WHO classification of tumors of the small intestine and ampulla
  • Currently on 5th edition, published in 2019
  • Based on histologic appearance, not molecular characteristics
WHO (2019)

    Malignant epithelial tumors ICD-O codes
  • Adenocarcinoma, NOS 8140/3
    • Mucinous adenocarcinoma 8480/3
    • Signet ring cell carcinoma 8490/3
    • Medullary carcinoma, NOS 8510/3
    • Adenocarcinoma, intestinal type 8144/3
    • Pancreatobiliary type adenocarcinoma 8163/3
    • Tubular adenocarcinoma 8211/3
  • Neuroendocrine tumor, NOS 8240/3
    • Neuroendocrine tumor, grade 1 8240/3
    • Neuroendocrine tumor, grade 2 8249/3
    • Neuroendocrine tumor, grade 3 8249/3
    • Gastrinoma, NOS 8153/3
    • Somatostatinoma, NOS 8156/3
    • Enterochromaffin cell carcinoid 8241/3
    • Extra-adrenal paraganglioma, NOS 8693/3
  • Neuroendocrine carcinoma, NOS 8246/3
    • Large cell neuroendocrine carcinoma 8013/3
    • Small cell neuroendocrine carcinoma 8041/3
  • Mixed neuroendocrine - nonneuroendocrine neoplasm (MiNEN) 8154/3
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