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Soft Tissue Tumors
Fibrolipoma
Author: Nat Pernick, M.D., PathologyOutlines.com, Inc.
Reviewer: David Lucas, M.D., University of Michigan Health Systems (January 2009)
Revised: 26 June 2009, last major update June 2009
Definition
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● Lipoma with prominent bundles of mature fibrous tissue traversing fatty lobules
Terminology
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● Not a WHO diagnosis
● Fibrovascular polyps of esophagus are also called fibrolipomas
● See also lipomatosis of nerve
Sites
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● Common in neck
Case reports
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● 48 year old woman with giant fibrolipoma of leg (Anticancer Res 2006;26:3649)
● 71 year old woman with 9 cm fibrolipoma of parotid gland (World J Surg Oncol 2006 Jun 2;4:28)
Gross images
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Intraoperative parotid tumor Encapsulated mass
Micro description
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● Lipoma with fibrous tissue component
Micro images
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Mature adipose tissue and Mature adipose tissue
dense bands of fibrosis and fibrous tissue
Differential Diagnoses
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● Spindle cell lipoma - shoulders/back, CD34+ bland spindle cells, pleomorphic cells
● Lipoma of hands, feet or buttocks - typically has dense fibrous tissue at these sites
● Well differentiated liposarcoma - atypical cells present in fibrous areas
End of Skin / Soft Tissue Tumors > Fibrolipoma
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