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Soft Tissue Tumors

Adipose tissue

Fibrolipoma


Reviewer: Charanjeet Singh, M.D. (see Reviewers page)
Revised: 10 November 2012, last major update June 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Lipoma with prominent bundles of mature fibrous tissue traversing fatty lobules

Terminology
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● Not a WHO diagnosis
● Fibrovascular polyps of esophagus are also called fibrolipomas
● See also lipomatosis of nerve

Sites
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● Common in neck
● Also present in head and neck (Contemp Clin Dent 2012;3:S112)

Case reports
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● 48 year old woman with giant fibrolipoma of leg (Anticancer Res 2006;26:3649)
● 71 year old woman with 9 cm fibrolipoma of parotid gland (World J Surg Oncol 2006;4:28)

Clinical images
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Intraoperative parotid tumor

Gross images
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Encapsulated mass

Micro description
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● Lipoma with fibrous tissue component

Micro images
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Mature adipose tissue and dense bands of fibrosis


Mature adipose tissue and fibrous tissue


Myxoid change

Differential diagnosis
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Spindle cell lipoma: shoulders/back, CD34+ bland spindle cells, pleomorphic cells
Lipoma of hands, feet or buttocks: typically has dense fibrous tissue
Well differentiated liposarcoma: atypical cells present in fibrous areas

End of Soft Tissue Tumors > Adipose tissue > Fibrolipoma


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