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Soft tissue
Fibroblastic / myofibroblastic tumors
Low-grade myofibroblastic sarcoma

Reviewer: Raul Gonzalez, M.D. (see Reviewers page)
Editor: Jerad M. Gardner, M.D.
Revised: 5 May 2014, last major update April 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

Definition
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Epidemiology
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Case reports
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Treatment
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Gross description
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Micro description
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Micro images
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Breast: H&E shows fascicular growth (fig 1A), alpha smooth muscle actin+ (fig 1B) and vimentin+ (insert), fibronectin+ matrix (fig 1C), type IV collagen negative (fig 1D)
Femur: hypocellular area with a proliferation of spindle cells with abundant intercellular collagen (A); hypercellular area with a proliferation of spindle cells with hyperchromatic enlarged nuclei and abundant intercellular collagen
Femur: additional images, including staining for smooth muscle actin

Case of the Week #310:
Desmin
Smooth muscle actin

Positive stains
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Negative stains
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Electron microscopy description
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Molecular / cytogenetics description
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Differential diagnosis
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Additional references
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End of Soft tissue > Fibroblastic / myofibroblastic tumors > Low-grade myofibroblastic sarcoma


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