Soft tissue
Benign vascular tumors
Intravascular papillary endothelial hyperplasia

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 19 September 2016, last major update November 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: Intravascular papillary endothelial hyperplasia [title]

Cite this page: Intravascular papillary endothelial hyperplasia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissuemasson.html. Accessed December 10th, 2016.
Definition / General
  • Reactive, not neoplastic, representing exuberant organization and recanalization of thrombus
  • In normal vessels but also varices, hemorrhoids, pyogenic granulomas, hematomas, angiosarcomas
Terminology
  • Also known as Masson's tumor
Sites
  • Dermis and subcutis of head and neck, lip, tongue, buccal mucosa
  • Also seen in heart, larynx and hypopharynx
Clinical Features
  • Pure type: within a dilated vascular space
  • Mixed type: with preexisting vascular disorder or in a hematoma
  • Extravascular form: rare and occurs in extravascular organizing hematoma
  • Usually presents as a red blue nodule in skin
Case Reports
Clinical Images
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Leg

Oral mucosa

Gross Description
  • Small, firm, reddish blue superficial masses in skin
Gross Images
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Small bowel

Micro Description
  • Intravascular lesion only, with papillary formations with hyaline or fibrous stalks, anastomosing vascular channels, plump endothelial cells; residual organizing thrombi
  • No necrosis, no atypia, no atypical mitotic figures
Micro Images
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Courtesy of Dr. Mark R. Wick



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Paranasal sinus lesion

Parotid gland lesion


Oral mucosa

Small bowel

Positive Stains
Differential Diagnosis