Soft tissue
Vascular: nonneoplastic
Papillary endothelial hyperplasia


Topic Completed: 1 November 2012

Revised: 9 September 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed search: Papillary endothelial hyperplasia [title]

Vijay Shankar, M.D.
Page views in 2018: 6,396
Page views in 2019 to date: 4,715
Cite this page: Shankar V. Papillary endothelial hyperplasia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissuemasson.html. Accessed September 18th, 2019.
Definition / general
  • Reactive, not neoplastic, representing exuberant organization and recanalization of thrombus
  • In normal vessels but also varices, hemorrhoids, pyogenic granulomas, hematomas, angiosarcomas
Terminology
  • Also known as Masson's tumor
Sites
  • Dermis and subcutis of head and neck, lip, tongue, buccal mucosa
  • Also seen in heart, larynx and hypopharynx
Clinical features
  • Pure type: within a dilated vascular space
  • Mixed type: with preexisting vascular disorder or in a hematoma
  • Extravascular form: rare and occurs in extravascular organizing hematoma
  • Usually presents as a red blue nodule in skin
Case reports
Clinical images
Images hosted on PathOut server:



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Oral mucosa

Gross description
  • Small, firm, reddish blue superficial masses in skin
Gross images
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Images contributed by K.V. Vinu Balraam, M.D.

COW #450



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Small bowel

Microscopic (histologic) description
  • Intravascular lesion only, with papillary formations with hyaline or fibrous stalks, anastomosing vascular channels, plump endothelial cells; residual organizing thrombi
  • No necrosis, no atypia, no atypical mitotic figures
Microscopic (histologic) images
Images hosted on PathOut server:

Images contributed by K.V. Vinu Balraam, M.D., COW #450



CD31

CD34

Ki67 / MIB1




Images contributed by Mark R. Wick, M.D.



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Paranasal sinus lesion

Parotid gland lesion


Oral mucosa

Small bowel

Positive stains
Differential diagnosis
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