Oral cavity & oropharynx
Other nonneoplastic
Pyogenic granuloma
Author: Nat Pernick, M.D.
Topic Completed: 1 November 2013
Minor changes: 30 December 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: Pyogenic granuloma oral cavity[mh]
Table of Contents
Definition / general | Treatment | Gross description | Microscopic (histologic) description | Differential diagnosisCite this page: Pernick N Pyogenic granuloma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/oralcavitypyogenicgranuloma.html. Accessed June 20th, 2021.
Definition / general
- Also called lobular capillary hemangioma, pregnancy tumor
- Most common tumor of gingiva
- Affects gingiva (usually maxilla) of children, young adults and pregnant women; associated with gingivitis
- Form of capillary hemangioma that regresses after pregnancy or undergoes fibrous maturation to resemble a fibroma; may be reactive (Am J Surg Pathol 1980;4:470)
Treatment
- Excision
Gross description
- Elevated, dark red lesion, variable ulceration
Microscopic (histologic) description
- Pedunculated lesion composed of granulation type tissue separated by bands of connective tissue
- Covering epithelium almost meets at base of lesion; has lobular arrangement of capillaries at base
- Lobules consist of discrete clusters of endothelial cells with indistinct to prominent lumina
- Superficial lesion may have secondary changes including stromal edema, capillary dilation, inflammation and granulation tissue reaction
Differential diagnosis
