Soft tissue

Vascular

Nonneoplastic

Papillary endothelial hyperplasia

Author: Vijay Shankar, M.D.

Topic Completed: 1 November 2012

Minor changes: 20 April 2021

Copyright: 2003-2022, PathologyOutlines.com, Inc.

PubMed search: Papillary endothelial hyperplasia [title]

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Table of Contents

Cite this page: Shankar V. Papillary endothelial hyperplasia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/softtissuemasson.html. Accessed January 19th, 2022.

Definition / general

Reactive, not neoplastic, representing exuberant organization and recanalization of thrombus
In normal vessels but also varices, hemorrhoids, pyogenic granulomas, hematomas, angiosarcomas

Terminology

Also known as Masson's tumor

Sites

Dermis and subcutis of head and neck, lip, tongue, buccal mucosa
Also seen in heart, larynx and hypopharynx

Clinical features

Pure type: within a dilated vascular space
Mixed type: with preexisting vascular disorder or in a hematoma
Extravascular form: rare and occurs in extravascular organizing hematoma
Usually presents as a red blue nodule in skin

Case reports

35 year old man with lesion of the paranasal sinus (Arch Pathol Lab Med 2000;124:1224)
39 year old man presented with progressive swelling over his midline scalp (Case of the Week #450)
39 year old man with painless enlargement of parotid gland (Indian J Pathol Microbiol 2011;54:226)
50 year old woman with small bowel lesion (Case Rep Gastroenterol 2010;4:124)
70 year old woman with mouth lesion (Case Rep Dermatol 2010;2:22)

Clinical images

Contributed by Mark R. Wick, M.D.

Images hosted on other servers:

Oral mucosa

Gross description

Small, firm, reddish blue superficial masses in skin

Gross images

Case #450, contributed by K.V. Vinu Balraam, M.D.

Images hosted on other servers:

Small bowel

Microscopic (histologic) description

Intravascular lesion only, with papillary formations with hyaline or fibrous stalks, anastomosing vascular channels, plump endothelial cells; residual organizing thrombi
No necrosis, no atypia, no atypical mitotic figures

Microscopic (histologic) images

Case #450, contributed by K.V. Vinu Balraam, M.D.