Other nonneoplastic lesions

Topic Completed: 1 August 2012

Revised: 26 April 2019

Copyright: 2003-2019,, Inc.

PubMed Search: gastric iron overdose

Elliot Weisenberg, M.D.
Page views in 2018: 1,374
Page views in 2019 to date: 802
Cite this page: Weisenberg E. Iron. website. Accessed July 16th, 2019.
Definition / general
  • Iron overdose may cause severe gastrointestinal necrosis and stricture
  • Therapeutic iron causes brown crystalline iron material in superficial gastric biopsies, often mixed with fibrinoinflammatory exudate
  • Usually (83%) associated with erosive or ulcerative mucosal injury, although this may also be due to other disorders (Am J Surg Pathol 1999;23:1241)
Positive stains
  • Prussian blue, Perl's iron
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