Other nonneoplastic lesions

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 2 November 2018, last major update August 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: gastric iron overdose
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Cite this page: Weisenberg, E. Iron. website. Accessed March 20th, 2019.
Definition / general
  • Iron overdose may cause severe gastrointestinal necrosis and stricture
  • Therapeutic iron causes brown crystalline iron material in superficial gastric biopsies, often mixed with fibrinoinflammatory exudate
  • Usually (83%) associated with erosive or ulcerative mucosal injury, although this may also be due to other disorders (Am J Surg Pathol 1999;23:1241)
Positive stains
  • Prussian blue, Perl's iron
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