Mixed epithelial and mesenchymal tumors

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Minor changes: 5 August 2020

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PubMed Search: Adenomyoma [title] uterus

Nat Pernick, M.D.
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Cite this page: Pernick N. Adenomyoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/uterusadenomyoma.html. Accessed September 26th, 2020.
Definition / general
  • A circumscribed nodular aggregate of benign endometrial glands surrounded by endometrial stroma, with leiomyomatous smooth muscle bordering the endometrial stromal component
  • See also adenomyosis (diffuse process), atypical polypoid adenoma
Essential features
  • Circumscribed lesion in the uterus
  • Benign endometrial glands and stroma bordered by leiomyomatus smooth muscle
  • Abnormal vaginal bleeding is the most common presenting feature
  • Adenomyoma, cystic adenomyoma, polypoid adenomyoma
  • Ages 22 - 60 years
Clinical features
  • Presents as abnormal vaginal bleeding
  • Severe cases in young women can manifest with infertility
  • Diagnosed with radiology and histopathology
Case reports
Clinical images

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Endometrial collection

Gross description
  • Soft to firm, grey white cut section
  • May show small cystic spaces filled with brownish fluid
  • Can be polypoid: polypoid adenomyoma
  • Can be predominantly cystic: cystic adenomyoma (Obstet Gynecol Sci 2014;57:176)
Microscopic (histologic) description
Microscopic (histologic) images

AFIP images
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Benign endometrial glands

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Various images

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Gross and micro images

Cytology description
Positive stains
Differential diagnosis
Additional references
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