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Uterus
Epithelial tumors
Adenomyoma
Reviewer: Jamie Shutter, MD, University of South Florida (see Reviewers page)
Revised: 21 September 2012, last major update June 2010
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.
Definition
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● Circumscribed nodular aggregate of benign endometrial glands surrounded by endometrial stroma with leiomyomatous smooth muscle bordering the endometrial stromal component.
● See also adenomyosis (diffuse process), atypical polypoid adenoma
Terminology
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● Also called adenomyomatous polyp
Sites
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● Predominantly intramural but can be submucosal and mimic endometrial polyps clinically
Clinical features
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● Any age
Treatment
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● Various hormonal drugs or minor surgical procedures
● Hysterectomy if deep myometrial involvement or if preserving fertility is not a concern (Arch Gynecol Obstet 2007;276:1)
Gross description (Macroscopy)
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● Well circumscribed and similar to leiomyoma but tends to be softer in consistency and more gray
Micro description (Histopathology)
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● Well circumscribed mass of benign endometrial glands in a myomatous stroma
● Often thick walled blood vessels
● May have 1-2 mitotic figures/10 HPF in endometrial stroma, but not in myometrium (Int J Gynecol Pathol 2006;25:361)
Micro images
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Benign endometrial glands without architectural complexity or cytologic atypia are surrounded by stroma that consists predominantly of smooth muscle. This lesion presented as a polyp projecting into the endometrial cavity.
Cytology description
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● May rarely have bizarre smooth muscle cells, but no necrosis or significant mitotic activity (Diagn Cytopathol 2005;32:288)
End of Uterus > Epithelial tumors > Adenomyoma
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