Breast - nonmalignant
Benign tumors / changes
Tubular adenoma of breast

Author: Hind Nassar, M.D. (see Authors page)

Revised: 14 August 2017, last major update April 2010

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Tubular adenoma [title] breast

Cite this page: Nassar, H. Tubular adenoma of breast. website. Accessed July 23rd, 2018.
Definition / general
  • Benign nodules formed by the compact proliferation of tubular structures with 2 cell layers
  • Tubular fibroadenoma: both components are conspicuous and are at least 10% of the lesion
Case reports
  • Excision, does not recur
Gross description
  • Solitary, well circumscribed, tan yellow, soft to firm mass
Microscopic (histologic) description
  • Closely packed uniform small tubules lined by single layer of epithelial cells and attenuated myoepithelium; sparse stroma
  • May have lymphocytic infiltrate, no atypia
Microscopic (histologic) images

Images hosted on PathOut server:

Ducts of uniform size

Tubular adenoma
pattern above,
pattern below

Images hosted on other servers:

Various images

Circumscribed tumor with packed acini

Tubular adenoma with ALH

p63 staining

Myosin staining

Cytology description
  • Three dimensional cohesive balls of ductal cells and tubular structures in highly cellular smears
  • Myoepithelial cells are present with sheets of ductal cells and as bipolar naked nuclei
  • May have staghorn pattern of ductal cells
  • No / scanty stroma (Cytopathology 1998;9:301)
Positive stains
Differential diagnosis