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CNS tumor
Astrocytic tumors
Gliosarcoma

Reviewer: Eman Abdelzaher, M.D., Ph.D. (see Reviewers page)
Revised: 28 April 2013, last major update March 2012
Copyright: (c) 2005-2013, PathologyOutlines.com, Inc.

General
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Radiology
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Radiology images
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MR images

Various images

Before surgery

Case reports
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Gross description
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Micro description
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Micro images
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Various images

Biphasic pattern

Reticulin stain


With carcinomatous areas

With prominent smooth muscle component

EGFR, p53


Figure 2


Fig 2A: biphasic with epithelioid and spindle cells
Fig 2B: markedly increased nuclear Ki-67 staining
Fig 2C: epithelioid component has strong GFAP staining
Fig 2D: spindle cells are SMA+ and surrounded by abundant reticulin fiber

Cytology description
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Positive stains
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Differential diagnosis
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End of CNS tumor > Astrocytic tumors > Gliosarcoma


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