Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Liver and intrahepatic bile ducts - tumor
Hepatocellular carcinoma
Fibrolamellar variant

Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 1 October 2013, last major update February 2012
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

See also   clear cell variant   below

General
=========================================================================

Clinical features
=========================================================================

Case reports
=========================================================================

Treatment
=========================================================================

Gross description
=========================================================================

Micro images
=========================================================================

Various images

Micro description
=========================================================================

Micro images
=========================================================================


Large, polygonal, densely eosinophilic tumor cells


Cords and clusters of tumor cells

Separated from the native liver paren-
chyma (right) by a thin fibrous capsule


Acinar structures, bile production

Foci of trabecular and acinar architecture

Tumor cells embedded in loose, myxoid stroma


Various images

Various images (figs e-h)


Various images


Pale bodies

Trichrome

CK7

CK20


HepPar

Ki-67

pCEA

Vimentin


Cytology description
=========================================================================

Cytology images
=========================================================================

Various images

Positive stains
=========================================================================

Negative stains
=========================================================================

Molecular description
=========================================================================

Electron microscopy description
=========================================================================

Differential diagnosis
=========================================================================



Clear cell variant of fibrolamellar carcinoma

Case reports
=========================================================================

Gross images
=========================================================================

Well circumscribed tumor

Micro images
=========================================================================

Classic fibrolamellar foci and clear cell foci

Antimitochondrial antibody stain

Electron microscopy images
=========================================================================

Distended membrane bound vesicles represent dilated mitochondria

End of Liver and intrahepatic bile ducts - tumor > Hepatocellular carcinoma > Fibrolamellar variant


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).