Lung - nontumor
Other nonneoplastic disease
Amyloidosis


Topic Completed: 1 October 2011

Minor changes: 27 May 2020

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PubMed search: pulmonary amyloidosis [title]

Related topics: nodular amyloid (amyloidoma)

Elliot Weisenberg, M.D.
Page views in 2019: 602
Page views in 2020 to date: 299
Table of Contents
Definition / general
Cite this page: Weisenberg E. Amyloidosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lungnontumoramyloid.html. Accessed June 4th, 2020.
Definition / general
  • Categorized by clinical syndrome (systemic or localized) and biochemical type
  • Currently 25 distinct types of amyloid fibers
  • Four major types are AL protein (amyloid light chain), AA protein (amyloid associated), ATTR protein (transthyretin, formerly prealbumin) and B2-microglobulin

In lung, four major clinical syndromes:
  • Systemic (generalized) pulmonary amyloid
  • Localized pulmonary amyloid (tracheobronchial and nodular forms)
  • Diffuse interstitial septal amyloidosis (diffuse parenchymal amyloid, interstitial, septal or vascular amyloid)
  • Pleural amyloid (very rare)
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