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General
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Radiology images
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Rosai-Dorfman disease: bone

Case reports
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Treatment
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Gross images
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Rosai-Dorfman disease: skin

Micro description
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Micro images
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Contributed by Dr. Mark R. Wick

Rosai Dorfman disease

S100


AFIP images:

Sinus histiocytosis with massive lymphadenopathy


Sinus histiocytosis with massive lymphadenopathy

Sinus histiocytosis with massive lymphadenopathy


Sinus histiocytosis with massive lymphadenopathy

Touch imprint of lymph node

Rosai-Dorfman disease: extranodal

Rosai-Dorfman disease: eye


Sinus histiocytosis with massive lymphadenopathy S100

Rosai-Dorfman disease: extranodal S100



Other images:

Histiocytes fill a nodal sinus


Extensive replacement of nodal architecture by pale staining cells

Distended sinus contains lymphocytes with ingested lymphocytes

Thyroid nodule



Contributed Anonymously:
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18 year old man with enlarged lymph node, which was excised

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S100

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CD1A



Cytology description
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Positive stains
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Negative stains
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Molecular description
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Differential diagnosis
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End of Lymph nodes - not lymphoma > Inflammatory disorders (non-infectious) > Sinus histiocytosis with massive lymphadenopathy



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