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Skin - Nonmelanocytic tumors

Adnexal tumors - eccrine sweat glands

Eccrine spiradenoma

Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 3 July 2012, last major update June 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Extremely painful lesions, anywhere in body
● Rarely transforms to high grade malignancy

Case reports
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● 73 year old with facial lesion (Indian J Dermatol Venereol Leprol 2008;74:541)

Gross description
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● Painful, slow growing solitary nodule, head/neck, adults > children
● Occasional multiple lesions, linear or Blaschkoid distribution

Micro description
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● Sharply circumscribed, lobular
● Very cellular
● Cells have scant cytoplasm
● High vascularity
● Variable lymphocytic infiltrate within lesion

Micro images
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Eccrine spiradenoma


Contributed by Dr. Amy Lynn, Toledo, Ohio

Electron macroscopy description
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● Epithelial and myoepithelial cells

Differential diagnosis
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● Cylindroma
● Synovial sarcoma
● Metastatic carcinoma
● Thymoma
● Cutaneous lymphadenoma

End of Skin - Nonmelanocytic tumors > Adnexal tumors - eccrine sweat glands > Eccrine spiradenoma

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