Skin - Nonmelanocytic tumors
Adnexal tumors - eccrine sweat glands
Eccrine spiradenoma

Author: Christopher Hale, M.D. (see Authors page)

Revised: 5 October 2016, last major update June 2012

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Eccrine spiradenoma [title]

Cite this page: Eccrine spiradenoma. website. Accessed May 22nd, 2017.
Definition / general
  • Extremely painful lesions, anywhere in body
  • Rarely transforms to high grade malignancy
Case reports
Clinical images

Breast skin, courtesy of Mark R. Wick, M.D.

Gross description
  • Painful, slow growing solitary nodule, head/neck, adults > children
  • Occasional multiple lesions, linear or Blaschkoid distribution
Microscopic (histologic) description
  • Sharply circumscribed, lobular
  • Very cellular
  • Cells have scant cytoplasm
  • High vascularity
  • Variable lymphocytic infiltrate within lesion
Microscopic (histologic) images

Images hosted on PathOut servers:

Contributed by Dr. Amy Lynn

Breast skin, courtesy of Mark R. Wick, M.D.

Images hosted on Flickr:

Eccrine spiradenoma

Electron microscopy description
  • Epithelial and myoepithelial cells
Differential diagnosis