Table of Contents
Definition / general | Gross images | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosis | Additional referencesCite this page: Gulwani H. Ischemia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/smallbowelischemia.html. Accessed September 22nd, 2023.
Definition / general
- Mucosal damage (initially) due to vascular occlusion or reduced blood flow associated with shunting
- Usually not due to atherosclerosis because of widely anastomosing blood supply
- Damage varies from none to hemorrhagic infarction
- Also ulceration, mucosal plaque, strictures
- Grossing bowel specimens with possible ischemia: dissect blood vessels and submit several sections to detect inflammation and thrombosis
Microscopic (histologic) description
- Early: lamina propria hemorrhage, superficial epithelial necrosis, preservation of deep crypts
- Later: ulceration with minimal inflammation, villous distortion, pyloric gland metaplasia progressing to full thickness infarct
- Late: strictures affecting muscularis propria
Differential diagnosis
- Crohn's disease: marked inflammatory infiltrate, no stricture of muscularis propria, no hemosiderin
Additional references