Small intestine & ampulla

Benign tumors / tumor-like conditions


Topic Completed: 1 August 2012

Minor changes: 19 November 2020

Copyright: 2003-2021,, Inc.

PubMed Search: Ischemia[TI] small bowel[TI]

Hanni Gulwani, M.B.B.S.
Page views in 2020: 6,952
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Cite this page: Gulwani H. Ischemia. website. Accessed December 8th, 2021.
Definition / general
  • Mucosal damage (initially) due to vascular occlusion or reduced blood flow associated with shunting
  • Usually not due to atherosclerosis because of widely anastomosing blood supply
  • Damage varies from none to hemorrhagic infarction
  • Also ulceration, mucosal plaque, strictures
  • Grossing bowel specimens with possible ischemia: dissect blood vessels and submit several sections to detect inflammation and thrombosis
Gross images

Images hosted on other servers:

Various images

Microscopic (histologic) description
  • Early: lamina propria hemorrhage, superficial epithelial necrosis, preservation of deep crypts
  • Later: ulceration with minimal inflammation, villous distortion, pyloric gland metaplasia progressing to full thickness infarct
  • Late: strictures affecting muscularis propria
Microscopic (histologic) images

Images hosted on other servers:

Various images

Differential diagnosis
  • Crohn's disease: marked inflammatory infiltrate, no stricture of muscularis propria, no hemosiderin
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